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DrugRepV browse page allows user to take a glance of the particular antiviral agent.Fields in the webpage is hylerlinked ot various external repositories like DrugBank, PubChem, Clinicaltrials.gov,and PubMed.User can explore the biological, Clinical, Chemical, and Structural details of every repurposed drug candidate.By clicking on the table header arrows, user can sort entries in ascending or descending order.


Total number of Records for Firefly luciferase assay are 26




DrugRepV_ID Antiviral Name
Drug type
Primary Indication
Secondary Indication
Strain
Pathways
Assay
Activity
Clinical Status
References
DrugRepV_2015Teicoplanin
Antiinfectives For Systemic Use
Bacterial infections
Ebola virus
Zaire strain-pEBOV
NA
Firefly luciferase assay
Decrease (50 %)
Approved
26585243
DrugRepV_2016Tamoxifen
Antineoplastic and Immunomodulating Agents
Breast cancer
Ebola virus
Zaire strain-pEBOV
NA
Firefly luciferase assay
Decrease (50 %)
Approved
26585243
DrugRepV_2017Clemastine
Respiratory System
Allergic rhinitis
Ebola virus
Zaire strain-pEBOV
NA
Firefly luciferase assay
Decrease (50 %)
Approved
26585243
DrugRepV_2018Toremifene
Antineoplastic and Immunomodulating Agents
Breast Cancer
Ebola virus
Zaire strain-pEBOV
NA
Firefly luciferase assay
Decrease (50 %)
Approved, Investigational
26585243
DrugRepV_2019Paroxetine
Nervous System
Major depressive disorder (MDD) | Panic disorder | Obsessive-compulsive disorder (OCD) | Social anxiety disorder (social phobia) | Generalized anxiety disorder (GAD) | Post-traumatic stress disorder (PTSD) | Premenstrual dysphoric disorder (PMDD)
Ebola virus
Zaire strain-pEBOV
NA
Firefly luciferase assay
Decrease (50 %)
Approved, Investigational
26585243
DrugRepV_2020Amiodarone
Cardiovascular agents
Anginal and Arrhythmia
Ebola virus
Zaire strain-pEBOV
NA
Firefly luciferase assay
Decrease (50 %)
Approved, Investigational
26585243
DrugRepV_2021Clomiphene
Genito Urinary System and Sex Hormones
Cancer
Ebola virus
Zaire strain-pEBOV
NA
Firefly luciferase assay
Decrease (50 %)
Approved
26585243
DrugRepV_2022Securinine
Anticancer
NA
Ebola virus
Zaire strain-pEBOV
NA
Firefly luciferase assay
Decrease (50 %)
NA
26585243
DrugRepV_2023Glafenine
Nervous System
Inflammatory disease
Ebola virus
Zaire strain-pEBOV
NA
Firefly luciferase assay
Decrease (50 %)
NA
26585243
DrugRepV_2024Oxeladin
Respiratory-Tract-agents
Cough
Ebola virus
Zaire strain-pEBOV
NA
Firefly luciferase assay
Decrease (50 %)
Withdrawn
26585243
DrugRepV_2025Pimethixene Maleate
Respiratory System
NA
Ebola virus
Zaire strain-pEBOV
NA
Firefly luciferase assay
Decrease (50 %)
Approved
26585243
DrugRepV_2026Artemisinin
Antiparasitic products, Insectisides and Repellents
Malaria
Ebola virus
Zaire strain-pEBOV
NA
Firefly luciferase assay
Decrease (50 %)
Experimental
26585243
DrugRepV_2027Indoprofen
Musculo-Skeletal System
Inflammatory disease
Ebola virus
Zaire strain-pEBOV
NA
Firefly luciferase assay
Decrease (50 %)
Withdrawn
26585243
DrugRepV_2028Iodoquinol
Genito Urinary System and Sex Hormones
Amoebiasis
Ebola virus
Zaire strain-pEBOV
NA
Firefly luciferase assay
Decrease (50 %)
Approved
26585243
DrugRepV_2029Levonordefrin
NA
Dental disorders
Ebola virus
Zaire strain-pEBOV
NA
Firefly luciferase assay
Decrease (50 %)
Approved
26585243
DrugRepV_2030Teicoplanin
Antiinfectives For Systemic Use
Bacterial infections
Ebola virus
Zaire strain-pEBOV
NA
Firefly luciferase assay
Decrease (90 %)
Approved
26585243
DrugRepV_2031Teicoplanin
Antiinfectives For Systemic Use
Bacterial infections
Ebola virus
Zaire strain-pEBOV
NA
Firefly luciferase assay
Decrease (50 %)
Approved
26585243
DrugRepV_2032Teicoplanin
Antiinfectives For Systemic Use
Bacterial infections
Ebola virus
Zaire strain-pEBOV
NA
Firefly luciferase assay
Decrease (87.5 %)
Approved
26585243
DrugRepV_2033Teicoplanin
Antiinfectives For Systemic Use
Bacterial infections
Ebola virus
Zaire strain-pEBOV
NA
Firefly luciferase assay
Decrease (95 %)
Approved
26585243
DrugRepV_2034Teicoplanin
Antiinfectives For Systemic Use
Bacterial infections
Ebola virus
Zaire strain-pEBOV
NA
Firefly luciferase assay
No significant effect (0 %)
Approved
26585243
DrugRepV_3745Falnidamol
NA
Solid Tumor
Ebola virus
1976
NA
Firefly luciferase assay
Decrease (50 %)
Investigational
25986249
DrugRepV_3746Falnidamol
NA
Solid Tumor
Ebola virus
2014
NA
Firefly luciferase assay
Decrease (50 %)
Investigational
25986249
DrugRepV_3747Falnidamol
NA
Solid Tumor
Lassa virus
NA
NA
Firefly luciferase assay
Decrease (50 %)
Investigational
25986249
DrugRepV_3748Amiodarone Hydrochloride
Cardiovascular agents
Anginal and Arrhythmia
Ebola virus
1976
NA
Firefly luciferase assay
Decrease (50 %)
Approved
25986249
DrugRepV_3749Amiodarone Hydrochloride
Cardiovascular agents
Anginal and Arrhythmia
Ebola virus
2014
NA
Firefly luciferase assay
Decrease (50 %)
Approved
25986249
DrugRepV_3750Amiodarone Hydrochloride
Cardiovascular agents
Anginal and Arrhythmia
Lassa virus
NA
NA
Firefly luciferase assay
Decrease (50 %)
Approved
25986249